The Malayer Boroujerd plutonic complex (MBPC) in western Iran, consists of a portion of a magmatic arc built by the northeast verging subduction of the Neo-Tethys plate beneath the Central Iranian Microcontinent (CIMC). Middle Jurassicaged felsic magmatic activity in MBPC is manifested by I-type and S-type granites. The mafic rocks include gabbroic intrusions and dykes and intermediate rocks are dioritic dykes and minor intrusions, as well as mafic microgranular enclaves (MMEs). MBPC Jurassic-aged rocks exhibit arc-like geochemical signatures, as they are LILE- and LREEenriched and HFSE- and HREE-depleted and display negative Nb Ta anomalies. The gabbro dykes and intrusions originated from metasomatically enriched garnet-spinel lherzolite [Degree of melting (fmel) * 15%] and exhibit negative Nd and positive to slightly negative eHf(T) (? 3.0 to - 1.6). The data reveal that evolution of Middle Jurassic magmatism occurred in two stages: (1) deep mantle-crust interplay zone and (2) the shallow level upper crustal magma chamber. The geochemical and isotopic data, as well as trace element modeling, indicate the parent magma for the MBPC S-type granites are products of upper crustal greywacke (fmel: 0.2), while I-type granites formed by partial melting of amphibolitic lower crust (fmel: 0.25) and mixing with upper crustal greywacke melt in a shallow level magma chamber [Degree of mixing (fmix): 0.3]. Mixing between andesitic melt leaving behind a refractory dense cumulates during partial crystallization of mantle-derived magma and lower crustal partial melt most likely produced MMEs (fmix: 0.2). However, enriched and moderately variable eNd(T) (- 3.21 to - 4.33) and high (87Sr/86Sr)i (0.7085 0.7092) in dioritic intrusions indicate that these magmas are likely experienced assimilation of upper crustal materials. The interpretations of magmatic activity in the MBPC is consistent with the role considered for mantle-derived magma as heat and mass supplier for initiation and evolution of magmatism in continental arc setting, elsewhere.