The DiSSCo Flanders consortium, with the goal of maturing and unlocking their DNA collections, identified 1) the need for actively sharing best practices regarding the management of DNA collections; and 2) a need for guidance on how to bring theory into practice. During the DiSSCo Flanders project, a DNA collection working group was created. The working group is open to all biodiversity related DNA collections associates in Belgium in diverse roles such as researchers, lab technicians, collection managers and data managers. Around 50 people from 13 organizations participate. The community is intended to be small and local, supported with an atmosphere of empowerment. Members are allowed to be passively (reading only) or actively engaged (joining events) with the group. The strength, as well as the challenge, of the DiSSCo Flanders community lies in its variety of contexts: universities, governmental and non-governmental research institutions, and museum institutes. This translates to a variety of DNA (or biobank) collection organizations such as decentralized or centralized; cold or room temperature storage; managed by an appointed curator or a lab technician. The working group organizes meetings and workshops, tours to each other's collections, and shares a mailing list and a document space. As its principal output the group has co-created a tool: The key to bringing DNA collections to the next level . The tool is available in its first version, with the ambition to test the tool and to provide online user consultancy sessions for its use as a next step. The working group and the co-created tool are positive examples of how a local community, sometimes managing smaller, or less conspicuous, types of Natural Science collections, can work together and use their unique perspectives, experiences and needs to contribute to the international Natural Science collection and biobanking communities.