AMORE (Advanced MOdeling and Research on Eutrophication) is an interdisciplinary consortium composed of biologists, bioengineers, biostatisticians and physical and ecological modelers aiming to develo Sustainability Science for the management of coastal zones in the Channel and the Southern Bight of the North Sea with a focus on the Belgian coastal zone(BCZ). Achievements performed since 1997 by the AMORE consortium demonstrated that the BCZ is a key pilot area for addressing effects of natural variability and human activity on coastal eutrophication and the sustainable use of economic activity. The BCZ is submitted to local (Scheldt, Ijzer) and transboundary (Seine, Somme, Rhine/Meuse) river inputs of anthropogenic nutrients (N and P) that modify the N:P:Si nutrient balance and the ecosystem structure of the coastal area, favoring the blooming of undesirable Phaeocystis colonies over diatoms. However the actual contribution of local river inputs to eutrophication in the BCZ and the related geographical spreading of Phaeocystis are largely determined by large-scale climatic phenomena such as the NAO (North Atlantic Oscillation) that determines the weather conditions over Northwestern Europe.