Natural products have served mankind as a source of medicine since or even before the recorded history existed. Vietnam, with its vast geographical diversity, boasts diverse botanical resources and possesses a strong ethno-botanical tradition. About 3200 medicinal plants grow in Vietnam with a third regarded as medicinally effective and the remaining two third as dubious to mildly effective. Those resources have a great potential to be developed as high-value healthcare products (food supplements). Nowadays, natural products are also gaining more interest in Western countries.