The first European mission to Venus (Venus Express) is described. It is based on a repeated use of the Mars Express design with minor modifications dictated in the main by more severe thermal environment at Venus. The main scientific task of the mission is global exploration of the Venusian atmosphere, circumplanetary plasma, and the planet surface from an orbiting spacecraft. The Venus Express payload includes seven instruments, five of which are inherited from the missions Mars Express and Rosetta. Two instruments were specially designed for Venus Express. The advantages of Venus Express in comparison with previous missions are in using advanced instrumentation and methods of remote sounding, as well as a spacecraft with a broad spectrum of capabilities of orbital observations.